Impacto del omega 3 en el tratamiento del trastorno depresivo: una revisión de la literatura
DOI:
https://doi.org/10.61661/congresso.cbmev.7.2024.112Palabras clave:
Ácidos grasos omega-3, Trastorno depresivo mayor, eficaciaResumen
Introducción: El Trastorno Depresivo Mayor (TDM) es una de las principales causas de discapacidad global. Sin embargo, las opciones de tratamiento actuales para la depresión siguen limitadas por la eficacia, el costo, la disponibilidad, los efectos secundarios y la aceptabilidad del paciente. En este escenario, el valor de los ácidos grasos poliinsaturados (PUFA) omega-3 sigue desatendido, aunque los beneficios de su uso ya están ampliamente respaldados por la evidencia de varios estudios. Objetivos: Examinar la evidencia empírica de la asociación entre los ácidos grasos omega-3 y la depresión, discutir posibles mecanismos de acción y explorar las implicaciones clínicas de tales hallazgos. Metodología: Se realizó una revisión narrativa, encuestando 28 artículos publicados entre 2019 y 2024. Resultados: Los estudios demostraron la efectividad del uso de omega-3 como terapia adyuvante para reducir la gravedad de la depresión. Sin embargo, la respuesta al tratamiento puede variar dependiendo de la presencia de comorbilidades en personas deprimidas, lo que refuerza la necesidad de estrategias de tratamiento personalizadas. Conclusión: Se necesita más investigación para mejorar la aplicación de la suplementación con AGPI omega-3 y mejorar las estrategias de medicina personalizada, aumentando así la efectividad de las intervenciones para esta población heterogénea de pacientes.
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Derechos de autor 2024 Caroline Kullmann Ribeiro, Sayra Catalina Coral Castro, Raul Costa Fabris, Alessandra Dalla Rosa Santini
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
El VI Congreso Brasileño de Medicina del Estilo de Vida permite que el(los) autor(es) mantenga(n) sus derechos de autor sin restricciones. Las publicaciones están bajo la licencia Creative Commons Attribution 4.0 International License - CC-BY
